Fm 2008 Orjinal Crack Cocaine

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    Fm 2008 Orjinal Crack Cocaine

      понедельник 13 апреля
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    Crack/cocaine users show more family problems than other substance users

    Generally, those who want a more intense, faster, cheaper high are attracted to crack. Some people begin with cocaine use and then transition to crack use when the habit of cocaine use is too expensive to maintain. According to the National Study on Drug Use and Health, in 2008, there were 1.9 million cocaine users, of which 359,000 used crack.

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    01/Jul/2014

    Crack/cocaine users show more family problems than other substance users

    DOI: 10.6061/clinics/2014(07)10

    OBJECTIVES: To evaluate family problems among crack/cocaine users compared with alcohol and other substance users. METHODS: A cross-sectional multi-center study selected 741 current adult substance users from outpatient and inpatient Brazilian specialized clinics. Subjects were evaluated with the sixth version of the Addiction Severity Index, and 293 crack users were compared with 126 cocaine snorters and 322 alcohol and other drug users. RESULTS: Cocaine users showed more family problems when compared with other drug users, with no significant difference between […]

    Keywords:Alcoholism; Cocaine; Crack Cocaine; Family Relations

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    Crack cocaine use and its relationship with violence and HIV

    01/Sep/2009

    Crack cocaine use and its relationship with violence and HIV

    DOI: 10.1590/S1807-59322009000900006

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    OBJECTIVES: To evaluate crack cocaine use practices, risk behaviors associated with HIV infection among drug users, and their involvement with violence. INTRODUCTION: HIV infections are frequent among drug users due to risky sexual behavior. It is generally accepted that crack cocaine use is related to increased levels of violence. Several reports point to an increase in violence from those involved in drug trafficking. Although HIV infections and risky sexual behavior among drug users have been quite well studied, there are […]

    Keywords:Crack Cocaine; Drug use; HIV; Risk behavior; Violence

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    dc.contributorSistema FMUSP-HC: Faculdade de Medicina da Universidade de São Paulo (FMUSP) e Hospital das Clínicas da FMUSP
    dc.contributor.authorTAKITANE, Juliana
    LEYTON, Vilma
    ANDREUCCETTI, Gabriel
    GJERDE, Hallvard
    VINDENES, Vigdis
    BERG, Thomas
    dc.date.issued2018
    dc.identifier.citationFORENSIC SCIENCE INTERNATIONAL, v.289, p.165-174, 2018
    dc.identifier.issn0379-0738
    dc.identifier.urihttp://observatorio.fm.usp.br/handle/OPI/28139
    dc.description.abstractCocaine is a potent stimulant drug widely abused that exists in two forms: as a hydrochloride salt and as a free base (crack). Cocaine and the inactive metabolite benzoylecgonine can be determined to reveal any kind of cocaine use, whereas the pyrolysis product anhydroecgonine methyl ester (AEME) can be determined to reveal crack smoking. There are many bioanalytical LC-MS/MS methods used for the determination of cocaine, metabolites and AEME. In these methods, chromatographic separation is usually performed by HPLC and sample preparation by solid phase extraction. For the first time, an UHPLC-MS/MS method for the simultaneous determination of cocaine, benzoylecgonine, cocaethylene and AEME in blood using a sample preparation by liquid-liquid extraction was developed and validated. Extraction recoveries were approximately 80%, 40%, 80% and 80%, respectively, obtained by using a mixture of MTBE/2-propanol (70: 30, v: v). Chromatographic separation was performed on a core shell biphenyl UHPLC column (100 x 2.1 mm ID, 1.7 mm particles). Method validation showed that the method is precise, accurate, robust and sensitive for its purposes. Limit of quantification (LOQ) concentrations were 0.7-1.5 ng/mL. The method was used to determine cocaine, benzoylecgonine, cocaethylene and AEME in 22 blood samples collected from victims of sudden, unexpected or violent death in Sao Paulo (Brazil). Concentrations >= LOQ were observed in 19, 21, 10 and 10 of these samples, respectively.
    dc.description.sponsorship · Coordination for the Improvement of Higher Education Personnel (CAPES) Foundation from Brazil [88881.133873/2016-01]
    · Legal Medical Institute of Sao Paulo (IML/SP)
    dc.language.isoeng
    dc.publisherELSEVIER IRELAND LTD
    dc.relation.ispartofForensic Science International
    dc.rightsrestrictedAccess
    dc.subject.otherchromatography-mass-spectrometry; anhydroecgonine methyl-ester; sample preparation techniques; lc-ms/ms; oral fluid; human plasma; bioanalytical methods; internal standards; biological samples; core-shell
    dc.titleDetermination of cocaine, metabolites and a crack cocaine biomarker in whole blood by liquid-liquid extraction and UHPLC-MS/MS
    dc.typearticle
    dc.rights.holderCopyright ELSEVIER IRELAND LTD
    dc.description.groupLIM/40
    dc.identifier.doi10.1016/j.forsciint.2018.05.030
    dc.type.categoryoriginal article
    dc.type.versionpublishedVersion
    hcfmusp.authorTAKITANE, Juliana:FM:
    hcfmusp.authorLEYTON, Vilma:FM:MLS
    hcfmusp.authorANDREUCCETTI, Gabriel:FM:
    hcfmusp.author.external · GJERDE, Hallvard:Oslo Univ Hosp, Dept Forens Sci, POB 4950, N-0424 Oslo, Norway
    · VINDENES, Vigdis:Oslo Univ Hosp, Dept Forens Sci, POB 4950, N-0424 Oslo, Norway
    · BERG, Thomas:Oslo Univ Hosp, Dept Forens Sci, POB 4950, N-0424 Oslo, Norway
    hcfmusp.origem.idWOS:000438589000028
    hcfmusp.publisher.cityCLARE
    hcfmusp.publisher.countryIRELAND
    hcfmusp.relation.reference · Abrahim A, 2010, J PHARMACEUT BIOMED, V51, P131, DOI 10.1016/j.jpba.2009.08.023
    · Armbruster D.A., 2008, CLIN BIOCHEM REV, V29, pS49
    · ARMBRUSTER DA, 1994, CLIN CHEM, V40, P1233
    · Barroso M, 2009, BIOANALYSIS, V1, P977, DOI 10.4155/BIO.09.72
    · Barroso M, 2015, BIOANALYSIS, V7, P1497, DOI 10.4155/bio.15.72
    · BASELT RC, 1983, J CHROMATOGR, V268, P502, DOI 10.1016/S0021-9673(01)95449-4
    · Benbrahim-Tallaa L, 2014, LANCET ONCOL, V15, P924, DOI 10.1016/S1470-2045(14)70316-X
    · Berg T, 2014, J CHROMATOGR A, V1344, P83, DOI 10.1016/j.chroma.2014.04.020
    · Berg T, 2011, J CHROMATOGR A, V1218, P9366, DOI 10.1016/j.chroma.2011.10.081
    · Butler AJ, 2017, DRUG ALCOHOL DEPEN, V180, P401, DOI 10.1016/j.drugalcdep.2017.08.036
    · Bylda C, 2014, ANALYST, V139, P2265, DOI 10.1039/c4an00094c
    · Bystrowska B, 2012, PHARMACOL REP, V64, P1337, DOI 10.1016/S1734-1140(12)70931-3
    · Cardona PS, 2006, FORENSIC SCI INT, V157, P46, DOI 10.1016/j.forsciint.2005.04.001
    · CONE EJ, 1995, J ANAL TOXICOL, V19, P459, DOI 10.1093/jat/19.6.459
    · CONE EJ, 1994, CLIN CHEM, V40, P1299
    · Cornish JW, 1996, ANNU REV PUBL HEALTH, V17, P259
    · Crime U. N. O. o. D. a., 2011, CRIM UN OFF DRUGS CR
    · D'Avila FB, 2016, J CHROMATOGR B, V1012, P113, DOI 10.1016/j.jchromb.2016.01.019
    · D'Avila FB, 2015, J PHARMACEUT BIOMED, V103, P67, DOI 10.1016/j.jpba.2014.10.026
    · Dams R, 2003, RAPID COMMUN MASS SP, V17, P1665, DOI 10.1002/rcm.1098
    · Dulaurent S, 2016, ANAL BIOANAL CHEM, V408, P1467, DOI 10.1007/s00216-015-9248-3
    · Fandino AS, 2002, J ANAL TOXICOL, V26, P567, DOI 10.1093/jat/26.8.567
    · Fandino AS, 2002, J MASS SPECTROM, V37, P525, DOI 10.1002/jms.310
    · Fekete S, 2012, J CHROMATOGR A, V1228, P57, DOI 10.1016/j.chroma.2011.09.050
    · Fekete S, 2011, J PHARMACEUT BIOMED, V54, P482, DOI 10.1016/j.jpba.2010.09.021
    · Fiorentin TR, 2018, J ANAL TOXICOL, V42, P69, DOI 10.1093/jat/bkx085
    · Fiorentin TR, 2017, J PHARMACOL TOX MET, V86, P60, DOI 10.1016/j.vascn.2017.04.003
    · Gergov M, 2003, J CHROMATOGR B, V795, P41, DOI 10.1016/S1570-0232(03)00498-7
    · GIORGI SN, 1995, J ANAL TOXICOL, V19, P392, DOI 10.1093/jat/19.6.392
    · Gritti F, 2012, J CHROMATOGR A, V1228, P2, DOI 10.1016/j.chroma.2011.07.014
    · Gritti F, 2010, J CHROMATOGR A, V1217, P1604, DOI 10.1016/j.chroma.2010.01.008
    · Gritti F, 2010, J CHROMATOGR A, V1217, P1589, DOI 10.1016/j.chroma.2009.12.079
    · Guha N, 2012, LANCET ONCOL, V13, P1192, DOI 10.1016/S1470-2045(12)70485-0
    · Hatsukami DK, 1996, JAMA-J AM MED ASSOC, V276, P1580
    · HEARN WL, 1991, J NEUROCHEM, V56, P698, DOI 10.1111/j.1471-4159.1991.tb08205.x
    · Hezinova V, 2012, ELECTROPHORESIS, V33, P653, DOI 10.1002/elps.201100410
    · Imbert L, 2014, FORENSIC SCI INT, V234, P132, DOI 10.1016/j.forsciint.2013.11.004
    · Ismaiel OA, 2010, J CHROMATOGR B, V878, P3303, DOI 10.1016/j.jchromb.2010.10.012
    · JATLOW PI, 1987, CLIN CHEM, V33, pB66
    · Jemal M, 2010, BIOMED CHROMATOGR, V24, P2, DOI 10.1002/bmc.1373
    · Jenkins AJ, 1997, J FORENSIC SCI, V42, P824
    · Jones R T, 1990, NIDA Res Monogr, V99, P30
    · Kintz P, 1997, HUM EXP TOXICOL, V16, P123, DOI 10.1177/096032719701600208
    · Kolbrich EA, 2006, J ANAL TOXICOL, V30, P501, DOI 10.1093/jat/30.8.501
    · Kole PL, 2011, BIOMED CHROMATOGR, V25, P199, DOI 10.1002/bmc.1560
    · Kraemer T, 2007, ANAL BIOANAL CHEM, V388, P1415, DOI 10.1007/s00216-007-1271-6
    · Langman LJ, 2009, J ANAL TOXICOL, V33, P447, DOI 10.1093/jat/33.8.447
    · Matuszewski BK, 2003, ANAL CHEM, V75, P3019, DOI 10.1021/ac020361s
    · Novakova L, 2013, J CHROMATOGR A, V1292, P25, DOI 10.1016/j.chroma.2012.08.087
    · Oiestad EL, 2007, CLIN CHEM, V53, P300, DOI 10.1373/clinchem.2006.074237
    · Oiestad EL, 2011, J ANAL TOXICOL, V35, P280, DOI 10.1093/anatox/35.5.280
    · Paul BD, 2005, BIOMED CHROMATOGR, V19, P677, DOI 10.1002/bmc.495
    · Pego AMF, 2017, FORENSIC SCI INT, V274, P83, DOI 10.1016/j.forsciint.2016.12.024
    · Rees KA, 2012, FORENSIC SCI INT, V217, P182, DOI 10.1016/j.forsciint.2011.11.001
    · Strano-Rossi S, 2008, ANAL CHIM ACTA, V606, P217, DOI 10.1016/j.aca.2007.10.053
    · Garcia RCT, 2012, TOXICOL SCI, V128, P223, DOI 10.1093/toxsci/kfs140
    · Thibert V, 2014, J CHROMATOGR B, V949, P16, DOI 10.1016/j.jchromb.2013.11.051
    · Valente MJ, 2010, J CHROMATOGR B, V878, P3083, DOI 10.1016/j.jchromb.2010.09.010
    · Vanstechelman S, 2012, J ANAL TOXICOL, V36, P136, DOI 10.1093/jat/bkr016
    · Wang S, 2007, J PHARMACEUT BIOMED, V43, P701, DOI 10.1016/j.jpba.2006.08.010
    · WARNER EA, 1993, ANN INTERN MED, V119, P226, DOI 10.7326/0003-4819-119-3-199308010-00009
    · Wieling J, 2002, CHROMATOGRAPHIA, V55, pS107, DOI 10.1007/BF02493365
    · Zancanaro I, 2012, FORENSIC SCI INT, V223, P208, DOI 10.1016/j.forsciint.2012.08.048
    dc.description.indexMEDLINE
    dc.identifier.eissn1872-6283
    hcfmusp.citation.wos1
    hcfmusp.affiliation.countryBrasil
    hcfmusp.affiliation.countryNoruega

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    • Artigos e Materiais de Revistas Científicas - LIM/40 [146]
      LIM/40 - Laboratório de Imunohematologia e Hematologia Forense
    • Artigos e Materiais de Revistas Científicas - FM/MLS [200]
      Departamento de Medicina Legal, Ética Médica e Medicina Social e do Trabalho - FM/MLS